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Germaben
II
| GERMABEN®
II |
INCI
Name
Propylene
Glycol (and) Diazolidinyl Urea (and) Methylparaben (and)
Propylparaben |
|
| DESCRIPTION |
| Germaben
II is a liquid preservative system with the following
composition: |
| GERMALL®
II (DIAZOLIDINYL UREA) |
30% |
| METHYLPARABEN |
11% |
| PROPYLPARABEN |
3% |
| PROPYLENE
GLYCOL |
56% |
|
|
| PROPERTIES |
Germaben
II is a clear viscous liquid with a characteristic mild
odor. It is readily soluble at a level of 1.0% in both
aqueous solutions and oil/water emulsions.
This product is a convenient, ready to-use complete
antimicrobial preservative system with a broad spectrum
of activity. The solubilized combination of Germall
II with methylparaben and propylparaben is effective
against Gram-positive and Gram-negative bacteria and
against yeast and mold.
Germaben II can be used without additional co-preservatives
and is compatible with essentially all cosmetic ingredients,
including surfactants and proteins. |
|
PHYSICAL
CHARACTERISTICS
(Not Necessarily Specifications) |
| Color |
Pale
to light yellow (APHA-100 max.) |
| Odor |
Characteristically
mild |
| Appearance |
Clear
viscous liquid |
| Nitrogen |
5.8-6.4% |
| Specific
Gravity |
1.1731-1.1839 |
| Total
Solids |
42.5-45.5% |
| Residue
on Ignition |
0.50%
maximum |
|
|
| APPLICATIONS |
All
the components of this product are permanently listed
by the EU.
Germaben II is an ideal preservative system for shampoos,
hair conditioners and emulsion products. It minimizes
the problems associated with incorporating solid parabens.
It dissolves completely in cosmetic formulations at
a 1.0% concentration over a wide pH range.
It can be conveniently incorporated into hot or cold
processed shampoos and into creams and lotions during
their manufacture. The preferred method of addition
of Germaben II is to add it slowly to the product with
good stirring just prior to the addition of the fragrance.
Germaben II has also been successfully used to preserve
troublesome formulations containing nonionic surfactants,
proteins, soluble collagen, aloe vera extracts and herbal
extracts. The broad spectrum of antimicrobiaI activity
obtained by the combination of Germall II with methylparaben
and propylparaben provides the preservation protection
necessary for sophisticated personal care products.
Germaben II is recommended to be used at a level of
up to 1.0%. This level provides to the product: 0.30%
Germall II, 0.11% methylparaben, 0.03% propylparaben
and 0.56% propylene glycol. Shampoos and liquid soaps
generally require less than 1.0% Germaben II. Although
Germaben II provides excellent antimicrobial preservation,
every developed or modified product should be challenge
tested to assure preservative efficacy. |
|
| TOXICOLOGICAL
DATA |
| The
toxicity of Germaben II is consistent with the expected
average of its component parts. Propylene glycol is
low in toxicity, but is known to cause minor eye and
skin irritation. Methylparaben and propylparaben, alone
or in combination, in concentrations >5.0% in propylene
glycol are known to cause severe eye and skin irritation.
The irritant effect of the Germall II in this mixture
is insignificant. |
| Toxicity
profile of Germaben II: |
| Acute
oral toxicity LD50 (rats) |
>2000
mg/kg |
| Acute
dermal toxicity LD50 (rabbits) |
>2000
mg/kg |
| Primary
skin irritation (rabbits) |
Moderate
skin irritant. (However, a 1.0% aqueous solution
of Germaben II is not a skin irritant) |
| Eye
irritation (rabbits) |
Severe
eye irritant at full strength. (However, a 1.0%
aqueous solution of Germaben II is not an eye
irritant) |
|
|
| |
Available
in small quantities. 16 oz. 32 oz. 64 oz. 1 gallon. Germaben
II Preservative, antimicrobial. Great for preserving cosmetics
containing aloe vera, green tea.
|
